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COMPARING SAFETY AND EFFICACY OF 3 DIFFERENT DOSES OF FENTANYL TO HEMODYNAMIC STRESS RESPONSE TO LARYNGOSCOPY AND INTUBATION

COMPARATIVE STUDY OF SAFETY AND EFFICACY OF THREE DIFFERENT DOSES OF FENTANYL ON HEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND TRACHEAL INTUBATION IN PATIENTSâ?? UNDER GENERAL ANAETHESIA.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/035113
Enrollment
90
Registered
2021-07-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: IV FENTANYL 2mcg/kg: COMPARED WITH IV FENTANYL 3mcg/kg AND IV FENTANYL 4mcg/kg in attenuating hemodynamic stress response to laryngoscopy and tracheal intubation during elective surgery

Sponsors

DEPARTMENT OF ANESTHESIOLOGY
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anaethesiology (ASA) grade I and II 2. Patients posted for elective surgery under GA requiring endotracheal intubation. 3.Hemodynamically stable patients with all routine investigationswithin normal limits. 4. Availability of informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with ASA physical status III or more. 2. Patients with major neurological, cardiac, respiratory, metabolic, renal, hepatic disease or with coagulation abnormalities. 3. Patients with anticipated difficult intubation. 4. Patients with known allergies to the study drug. 5. Patients who are not giving consent for above study. 6 .Patients with body mask index more than 30. 7.Patients posted for emergency procedure. 8. Pregnant patients.

Design outcomes

Primary

MeasureTime frame
To compare and choose the better dose of fentanyl for pressor response suppression during laryngoscopy and tracheal intubation. Timepoint: 20 MINUTES—

Secondary

MeasureTime frame
To compare Heart rate(HR), Systolic blood pressure (SBP), Diastolic blood pressure (DBP), Mean arterial blood pressure (MAP), Peripheral oxygen saturation (SpO2), Respiratory rate (RR). Timepoint: 20 MINUTES;To compare sedation score in three groupsTimepoint: 30 minutes post extubation;To study any side effects of the three different dosage. Timepoint: entire surgical duration—

Countries

India

Contacts

Public ContactDR DIPANJALI MAHANTA

DR D Y PATIL MEDICAL COLLEGE HOSPITAL AND RESEARCH CENTRE PUNE

drbhavinishah71@gmail.com9850829994

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026