Health Condition 1: M341- CR(E)ST syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 20-60 years; 2. Patients fulfil the criteria of Vatarakta (Scleroderma); 3. Patients with Limited Cutaneous Systemic Sclerosis (LCSS); 4. CREST (Calcinosis, Raynaudâ??s, Oesophageal involvement, Sclerodactyly and Telangiectasia) Syndrome; 5. Chronicity between 6 weeks to 10 years with not less than 30% involvement of body surface.; 6. Digital Ulcers; 7. Patients who are fit for Basti Karma and Virechana Karma
Exclusion criteria
Exclusion criteria: 1. Age less than 20 and more than 60 years; 2. Diffuse Cutaneous Systemic Sclerosis; 3. Patients with traumatic, malignant and chronic wound; 4. Pregnancy & lactating mothers; 5. Any other systemic disorders; 6. Patients who are unfit for Basti Karma and Virechana Karma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subjective parameters: 1.Twak Kathinta (Skin Hardening) 2.Twak Vaivarnyata (Raynaudâ??s Phenomenon) 3.Sandhishotha (Joint Swelling) 4.Stabdhata (Stiffness) 5.Paka / Twak Lohita (Digital Ulcer) Associated Symptoms: 1.Shula (Pain) 2.Kandu (Itching) 3.Daha (Burning sensations) 4.Jwara (Fever)Timepoint: 30 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Objective parameters: 1.Modified Rodnan Skin Score (mRSS) 2.Involvement of Body Surface Area 3.Digital Ulcer Size 4.Discharge 5.ESR 6.Antinuclear Antibody Titers 7.CRPTimepoint: 30 days | — |
Countries
India
Contacts
PATANJALI BHARTIYA AYURVIGYAN EVAM ANUSANDHAN SANSTHAN