Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: CLONIDINE: 1 microgram/kg of clonidine diluted in 20 ml normal saline over a period of 10 mins.
Control Intervention1: Magnesium sulfate: 30mg/kg of magnesium sulfate in 20 ml normal sa
Sponsors
DR D Y PATIL MEDICAL COLLEGE AND RESEARCH CENTRE
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA grade I and II patients. 2. Age between 20 and 60 years. 3. Hemodynamically stable patients. 4. Patients undergoing laparoscopic abdominal surgeries. 5. Availability of informed consent and willingness of the patient to be a part of the study.
Exclusion criteria
Exclusion criteria: 1. Patients with ASA physical status III or more. 2. Patients below 20 years and above 60 years of age. 3. Patient with cardiovascular, neurological, renal and respiratory comorbidities. 4. Patients allergic to any drug used in the study. 5. Patients with hypermagnesemia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| heart rate, systolic and diastolic blood pressure, mean arterial pressure, end tidal carbon dioxideTimepoint: heart rate, systolic and diastolic blood pressure, mean arterial pressure, end tidal carbon dioxide baseline, after premedications, during intubation, after pneumoperitoneum, 10 mins,20 mins, every 20 mins till end of surgery, 30 mins, 1 hour, 4 hours in recovery room | — |
Secondary
| Measure | Time frame |
|---|---|
| sedation and pain scoreTimepoint: on arrival and after 30 mins,1 hour,2 hours,3 hours,and 4 hours in the recovery room with the help of VAS Scale and Ramsay sedation score. | — |
Countries
India
Contacts
Public ContactDr Krusha Shah
DR. D.Y.PATIL MEDICAL COLLEGE CENTRE AND RESEARCH CENTRE
Outcome results
None listed