Skip to content

comparing methods of non invasive ventilation after pediatric cardiac surgery

Comparative effect of High Frequency Nasal Cannula and Non Invasive Ventilation on the work of breathing and postoperative pulmonary complication after pediatric congenital cardiac surgery : A prospective randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/035055
Enrollment
63
Registered
2021-07-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: RAMS CANNULA NIV: non invasive ventilation delivered by ventilator through the RAMS CANNULA as the interface post extubation till p/f ratio 300 Intervention2: SIPAP: or Sigh PAP device
SIPAP: high frequency nasal cannula to deliver high humidified oxygen at high oxygen concentration
or Sigh PAP device is a form of bilevel PAP to deliver two levels of positive airway pressure for better lung recruitment post extubation till p/f ratio 300

Sponsors

PGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: post cardiac surgery belonging to RACHS GROUP 1,2

Exclusion criteria

Exclusion criteria: Neonates Preoperative respiratory compromise Preoperative requirement of mechanical ventilation Emergency surgery Residual anatomical defects etc. Diaphragmatic palsy

Design outcomes

Primary

MeasureTime frame
compare the magnitude of decrease in respiratory workload by HFNC, NIPPV and SIPAP as assessed using diaphragmatic thickening fraction and 2D longitudinal strain.Timepoint: at extubation, D1, D2, D3,D4,D5,D6,D7,D8,D9,D10

Secondary

MeasureTime frame
Changes in oxygenation (P/F ratio; ROX index) Proportion of patients that require reintubation till 48 hours post extubation and until discharge from ICU. Switching to other treatment options or premature treatment discontinuation(NIV/HFNC failure) Incidence of complications like atelectasis, collapse, pneumothorax, abdominal distension, feed intolerance,etc. Correlation between Strain and DTF as a measure of diaphragmatic function Compliance for the device Timepoint: at extubation, D1, D2, D3,D4,D5,D6,D7,D8,D9,D10

Countries

India

Contacts

Public ContactALISHA GOEL

Proffesor, Department of Anesthesia, PGIMER CHANDIGARH

bhupeshkr@yahoo.com07087009511

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026