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Evaluation of the efficacy of Vitamin C to prevent Gingival Repigmentation after surgical Depigmentation

Evaluation of the efficacy of Vitamin C to prevent Gingival Repigmentation after surgical Depigmentation and its correlation with Tyrosinase gene activity

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/035019
Enrollment
64
Registered
2021-07-20
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Surgical gingival depigmentation: Surgical gingival depigmentation followed by administration of Vitamin injection at 2weeks, 4weeks and then monthly intervals for 6months Control Inter

Sponsors

Rizwan Sanadi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects having physiological gingival hyperpigmentation [score 2 and score 3 of Dummett-Gupta Oral Pigmentation Index (DOPI) 1964)]. 2. Systemically healthy individuals with aesthetic concern.

Exclusion criteria

Exclusion criteria: 1.Subjects taking medications which may cause gingival melanin hyperpigmentation. 2.Smokers, drug addicts or Alcoholics. 3.Subjects with autoimmune or endocrine disorders. 4.Pregnant and lactating mothers.

Design outcomes

Primary

MeasureTime frame
Prevention of repigmentation after surgical gingival depigmentationTimepoint: Baseline to 1 yeaar follow up—

Secondary

MeasureTime frame
Uneventful healingTimepoint: Baseline to 1year follow up—

Countries

India

Contacts

Public ContactDr Revati Deshmukh

Bharati Vidyapeeth Deemed to be University Dental College & Hospital, Pune

rvt_deshmukh@yahoo.com9822014613

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026