EFFECT OF A SMALL DOSE OF KETAMINE ON POST CAESAREAN PAIN AND ITS INCIDENTAL EFFECT ON POST CAESAREAN MOOD IN SOUTH INDIAN WOMEN

Effect of sub anesthetic bolus dose of ketamine on postoperative pain in caesarean section and its incidental effect on postpartum blues in south Indian parturients.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/07/034985

Enrollment

Registered

2021-07-19

Start date

Unknown

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: K group ( KETAMINE GROUP) : K GROUP DOSE-0.3mg/kg of S- ketamine bolus dose after the delivery of the baby Control Intervention1: P GROUP: 2ML OF NORMAL SALINE INSTEAD OF KETAMINE AF

Eligibility

Inclusion criteria

Inclusion criteria: Only those patients with ASA physical status 1 or 2 patients undergoing elective Caesarean Section under spinal anaesthesia will be included in this study.

Exclusion criteria

Exclusion criteria: Those patients with characteristics and health conditions below will be excluded from the study. • ASA physical status 3 and 4 • Surgeries taking more than 2 hours duration • History of chronic pain • Regular medication with analgesics • Psychiatric disorder

Design outcomes

Primary

Measure	Time frame
1. To compare and evaluate Pain Score at 6, 12 and 24 hours post operatively 2. To compare total analgesic requirement in the first 24 hours 3.Screening of postpartum blues in the postpartum period of Day 1 and Day 7 as per Edinburgh Postnatal depression Scale between the ketamine group and placebo groups. 4. To compare incidence of Postoperative Nausea and Vomiting in the first 24 hours. 5. To compare patient comfort and satisfaction at 24 hours of surgeryTimepoint: 1. To compare and evaluate Pain Score at 6, 12 and 24 hours post operatively 2. Total analgesic requirement in the first 24 hours 3.Screening of postpartum blues in the postpartum period of Day 1 and Day 7 4. Incidence of Postoperative Nausea and Vomiting in the first 24 hours. 5.Patient comfort and satisfaction at 24 hours of surgery	—

Measure

Time frame

1. To compare and evaluate Pain Score at 6, 12 and 24 hours post operatively 2. To compare total analgesic requirement in the first 24 hours 3.Screening of postpartum blues in the postpartum period of Day 1 and Day 7 as per Edinburgh Postnatal depression Scale between the ketamine group and placebo groups. 4. To compare incidence of Postoperative Nausea and Vomiting in the first 24 hours. 5. To compare patient comfort and satisfaction at 24 hours of surgeryTimepoint: 1. To compare and evaluate Pain Score at 6, 12 and 24 hours post operatively 2. Total analgesic requirement in the first 24 hours 3.Screening of postpartum blues in the postpartum period of Day 1 and Day 7 4. Incidence of Postoperative Nausea and Vomiting in the first 24 hours. 5.Patient comfort and satisfaction at 24 hours of surgery

—

Secondary

Measure	Time frame
Screening of postpartum blues in the postpartum period of Day 1 and Day 7 4. Incidence of Postoperative Nausea and Vomiting in the first 24 hours. 5.Patient comfort and satisfaction at 24 hours of surgeryTimepoint: Postpartum blues in the postpartum period of Day 1 and Day 7 4. Incidence of Postoperative Nausea and Vomiting in the first 24 hours. 5.Patient comfort and satisfaction at 24 hours of surgery	—

Measure

Time frame

Screening of postpartum blues in the postpartum period of Day 1 and Day 7 4. Incidence of Postoperative Nausea and Vomiting in the first 24 hours. 5.Patient comfort and satisfaction at 24 hours of surgeryTimepoint: Postpartum blues in the postpartum period of Day 1 and Day 7 4. Incidence of Postoperative Nausea and Vomiting in the first 24 hours. 5.Patient comfort and satisfaction at 24 hours of surgery

—

Countries

India

Contacts

Public ContactAPARNA SATISH

KASTURBA MEDICAL COLLEGE,MANIPAL

raoamruts@gmail.com9986444044

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026