TO COMPARE COMBINATION OF PREGABALIN-CELECOXIB VERSUS PREGABALIN FOR REDUCING PAIN IN TOTAL KNEE ARTHROPLASTY

COMPARISON OF A COMBINATION OF PREGABALIN-CELECOXIB VERSUS PREGABALIN ALONE FOR PRE EMPTIVE ANALGESIA IN TOTAL KNEE ARTHROPLASTY

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/07/034919

Enrollment

100

Registered

2021-07-16

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue

Interventions

Control Intervention1: PREGABALIN CELECOXIB: TO COMPARE BETWEEN COMBINATION OF TAB.PREGABALIN 150mg AND TAB CELECOXIB 400mg AND TAB PREGABALIN 150mg ALONE IN PRE EMPTIVE ANALGESIA IN TOTAL KNEE ARTHRO

Eligibility

Inclusion criteria

Inclusion criteria: ASA Physical Status 1 and 2

Exclusion criteria

Exclusion criteria: Patient refusal Patient on anticoagulants Psychiatric disorders Drug allergy Neuromuscular disease Contra indication to neuraxial anaesthesia History of gastric ulcers Patients with lactose or galactose intolerance

Design outcomes

Primary

Measure	Time frame
HEMODYNAMIC PARAMETERS(HR,BP,SpO2,RR) VAS SCORE KNEE FUNCTIONAL OUTCOME MOBILIZATION AND ADHERENCE TO ERASTimepoint: 30 minutes, 1st hour 2nd hour 4th hour 6th hour 12th hour 24th hour	—

Secondary

Measure	Time frame
POST OPERATIVE ANALGESIC USE DURATION OF HOSPITAL STAY SIDE EFFECTS OF THE STUDY DRUGSTimepoint: 24 hours postoperative	—

Countries

India

Contacts

Public ContactBinsha K Hamza

Kasturba Medical College Mangalore

drupadya@hotmail.com9845225340

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026