Health Condition 1: K352- Acute appendicitis with generalized peritonitis
Conditions
Interventions
Intervention1: General Anaesthesia: INDUCTION OF GENERAL ANAESTHESIA
Before induction patients in group D will receive I.V Dexmedetomidine at 1mcg/kg as loading dose over 10 min and then continuous in
Sponsors
Shilpa Sarang Kore
Eligibility
Inclusion criteria
Inclusion criteria: patients undergoing elective laparoscopic surgeries patients undergoing elective laparoscopic surgeries under general anaesthesia haemodynamically stable patients with routine investigations within normal limits without any other comorbidities availability of informed written consent
Exclusion criteria
Exclusion criteria: Patient refusal Patients with ASA III or more Age below 18 years and above 60 years patients posted for emergency surgeries patients who are on drugs that can influence hemodynamic and autonomic functions. patients with predictably difficult airway or difficult intubation history of cardiac disease and neurologic disease pregnancy and breast feeding women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To Compare the efficacy of dexmedetomidine v/s fentanyl based general anaesthesia technique in attenuating neuroendocrine and hemodynamic stress response in laparoscopic surgeries.Timepoint: Every 5 minutes post intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| Observe side effects of dexmedetomidine and fentanyl and their managementTimepoint: Anytime after administrating drugs until 24 hours post op;to investigate the effects of dexmedetomidine and fentanyl on modulation of neuroendocrine stress response during elective laparoscopic surgeriesTimepoint: half an hour post intubation, 2 hours post extubation;To study the effects of dexmedetomidine and fentanyl on hemodynamic parameters during perioperative periodTimepoint: Every five minutes post intubation | — |
Countries
India
Contacts
Public ContactDr SHILPA SARANG KORE
Dr DY Patil Medical College And Research Centre
Outcome results
None listed