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A comparison of bolus and continuous feeding with respect to vasopressor requirements in sepsis and septic shock patients.

Impact of continuous versus bolus enteral nutrition on vasopressor support in patients of sepsis and septic shock ; a comparative analysis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/07/034796
Enrollment
80
Registered
2021-07-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A419- Sepsis, unspecified organism

Interventions

None listed

Sponsors

FORTIS ESCORTS HEART INSTITUTE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adults > 18 years of age 2.Patients of sepsis and septic shock as per sepsis 3 definition 3.Admitted to ICU with Nasogastric, Orogastric or Nasojejunal tube for enteral feeding. 4.Patient informed and consented to be included in the study. 5.Patient will be enrolled in the study within 6 hours of start of enteral feeding.

Exclusion criteria

Exclusion criteria: 1.Patient on parenteral nutrition 2.Active bowel obstruction as diagnosed clinically 3.Mesenteric ischemia 4.GI infection precluding Enteral Nutrition 5.Any other contraindications to Enteral nutrition

Design outcomes

Primary

MeasureTime frame
1.change in vasopressor dose over 1st 72 hours of EN 2.Addition of any vasopressor drug in order to maintain MAP â?¥65mm of Hg. 3.Serum lactate level as a marker of hypoperfusion Timepoint: every 12th hour until 72 hours

Secondary

MeasureTime frame
Incidence of gastro intestinal tract complications 1. Dairrhoea defined as having â?¥ 3 stools (loose/ liquid), with a stool weight 200 grams per day 2.Vomiting 3.Gastric residual volume , defined as aspirate volume 500 ml from feeding tube. 4.Incidences of NOMI & NOBN 5.ICU length of stay 6.Discharged from hospital or Death. Timepoint: till 72 hours and then during discharge from ICU or hospital

Countries

India

Contacts

Public ContactDR RISHABH KUMAR

FORTIS ESCORTS HEART INSTITUTE

drrishabhmittal@gmail.com8373918487

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026