Health Condition 1: A419- Sepsis, unspecified organism
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Adults > 18 years of age 2.Patients of sepsis and septic shock as per sepsis 3 definition 3.Admitted to ICU with Nasogastric, Orogastric or Nasojejunal tube for enteral feeding. 4.Patient informed and consented to be included in the study. 5.Patient will be enrolled in the study within 6 hours of start of enteral feeding.
Exclusion criteria
Exclusion criteria: 1.Patient on parenteral nutrition 2.Active bowel obstruction as diagnosed clinically 3.Mesenteric ischemia 4.GI infection precluding Enteral Nutrition 5.Any other contraindications to Enteral nutrition
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.change in vasopressor dose over 1st 72 hours of EN 2.Addition of any vasopressor drug in order to maintain MAP â?¥65mm of Hg. 3.Serum lactate level as a marker of hypoperfusion Timepoint: every 12th hour until 72 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of gastro intestinal tract complications 1. Dairrhoea defined as having â?¥ 3 stools (loose/ liquid), with a stool weight 200 grams per day 2.Vomiting 3.Gastric residual volume , defined as aspirate volume 500 ml from feeding tube. 4.Incidences of NOMI & NOBN 5.ICU length of stay 6.Discharged from hospital or Death. Timepoint: till 72 hours and then during discharge from ICU or hospital | — |
Countries
India
Contacts
FORTIS ESCORTS HEART INSTITUTE