Health Condition 1: F20- Schizophrenia
Conditions
Interventions
Intervention1: High Definition Trans-Cranial Direct Current Stimulation (HDtDCS): The central active anode electrode will be placed over the medial prefrontal Cortex/ d ACC (FZ) which will be surround
Sponsors
Central Institute Of Psychiatry
Eligibility
Inclusion criteria
Inclusion criteria: 1.Diagnosis of Schizophrenia using Diagnostic Criteria for Research (DCR) of International Classification of Disease-10th edition (ICD-10, World Health Organization,1992) 2.Duration of illness to be more than or equal to two years. 3.Age between 18- 60 years of either sex 4.The Positive and Negative Syndrome Scale for Schizophrenia (PANSS) negative symptoms score of more than 15 5.Scale for Assessment of Negative Symptoms (SANS) score more than 20 6.Right-handed 7.Educated upto class VIII or above 8.Patients giving written informed consent.
Exclusion criteria
Exclusion criteria: 1.Presence of co-morbid neurological or other psychiatric disorder(s). 2.Patient with co morbid substance dependence, except nicotine and caffeine. 3.Having any metallic implants/parts in body 4.Subjects who have received ECT in past 6 months. 5.Colour blind
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in scores on negative and cognitive symptoms after application of HDtDCS.Timepoint: 1. At baseline 2. At the end of 2 weeks 3. At the end of 4 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in fMRI activation of Pre Frontal Cortex using cognitive task and change in resting state functional connectivity at baseline and after application of HDtDCS.Timepoint: 1. At baseline 2. At the end of 2 weeks | — |
Countries
India
Contacts
Public ContactDr Nishant Goyal
Central Institute Of Psychiatry
Outcome results
None listed