to avoid vomiting in the first hour after key hole surgery for gall bladder removal in female patient.

COMPARATIVE STUDY OF ORAL OLANZEPINE VERSUS ORAL ONDANSETRON FOR PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING IN FEMALE PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY UNDER GENERAL ANAESTHESIA

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/07/034747

Enrollment

160

Registered

2021-07-09

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K95- Diseases of the digestive system

Interventions

Intervention1: OLANZEPINE: 5MG 4 HRS BEFORE SURGERY Control Intervention1: ONDANSETRON: 16MG 1HOUR BEFORE SURGERY

Eligibility

Inclusion criteria

Inclusion criteria: FEMALE PATIENT POSTED FOR ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY UNDER GENERAL ANAESTHESIA ASA 1 AND 2 PATIENT WHO GIVE INFORMED WRITTEN CONSENT

Exclusion criteria

Exclusion criteria: PATIENT REFUSAL TO GIVE WRITTEN CONSENT PATIENTS WITH PREEXISTING NAUSEA VOMITING OR MOTION SICKNESS PATIENTS WHO RECEIVED OPIOIDS OR DRUGS WITH KNOWN ANTIEMETIC PROPERTIES BEFORE SURGERY PREGNANCY

Design outcomes

Primary

Measure	Time frame
PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITINGTimepoint: MEASURED IMMEDIATELY AFTER SURGERY UPTO 24HRS AFTER SURGERY	—

Secondary

Measure	Time frame
TO KNOW SEDATION EFFECTTimepoint: 6 MONTHS;TO KNOW SIDE EFFECTS LIKE HYPOTENSION DIZZINESSTimepoint: 6MONTHS	—

Countries

India

Contacts

Public ContactDRHEMA H A

Hassan Institute of Medical Sciences

hemalakshmeesha@gmail.com9448940699

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026