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A comparative evaluation of the effect of two types of mouthwashes on the bacterial flora and health of the oral cavity

A comparative evaluation of Silver-Nano particle containing Mouthwash with Chlorhexidine on the colonization of microflora and gingival health: A Double-blind RCT

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/034736
Enrollment
80
Registered
2021-07-09
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K038- Other specified diseases of hard tissues of teeth

Interventions

Intervention1: Silver Nano-particle containing mouthrinse (NanOlife Dhanvantri Nano Ayushodi Pvt. Ltd.): The participants will start using mouthrines after 4 weeks of bonding. They will be using the m

Sponsors

Dr Shrestha Bisht
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Subjectsââ?¬• willingness to participate. 2.The indication for fixed orthodontic treatment, between 15-30years of age. 3.Lack of dental caries and/or restorations. 4.Absence of severe dental plaque (plaque index ââ?°Â¤ 20% measured by Oââ?¬•Leary index using plaque disclosing agent) / severe gingival inflammation/severe periodontal condition. 5.Absence of any systemic diseases. 6.Not having used any mouth rinses for at least 1 month before the initiation of the study. 7.Not on antibiotics and/or anti inflammatory drugs in the past 3 months

Exclusion criteria

Exclusion criteria: 1.History of previous periodontal treatments. 2.Active periodontal diseases. 3.Mouth breathing or any other problems which could affect oral microbial flora. 4.Presence of dental crowding( >4mm). 5.Sign of sensitivity to mouthwashes during the study

Design outcomes

Primary

MeasureTime frame
To compare the effectiveness of silver nanoparticle mouthwash and Chlorhexidine mouthwash on gingival health and count of microorganisms during fixed orthodontic treatment.Timepoint: 3 months

Secondary

MeasureTime frame
To evaluate the effectiveness of silver nanoparticle mouthwash on gingival health and colonization of microorganisms during fixed orthodontic treatment. Timepoint: 3 months

Countries

India

Contacts

Public ContactDr Shrestha Bisht

Subharti Dental College & Hospital

drpradeepraghav@gmail.com9837175914

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026