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Comparison of neuromuscular blockade and in recovery characteristics of Cis-Atracurium Besylate and Atracurium Besylate

cis atracurium besylate versus atracurium besylate: comparison of neuromuscular blockade and recovery characteristics

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/034724
Enrollment
60
Registered
2021-07-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Cisatracurium Besylate 0.2mg/kg loading dose followed by 0.03mg/kg maintenance dose: TO assess the ï?? Time of onset ï?? Intubating conditions ï?? Duration of action of loading dose ï

Sponsors

Government medical college Baroda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • ASA I and ASA II patients • Aged from 18 to 65 years old • Either genders • Patients scheduled for surgeries performed under general anaesthesia of an anticipated duration of 1.5-2.5 hrs

Exclusion criteria

Exclusion criteria: • Patients unwilling to participate • Patients with difficult airway. • Patients with systemic disorders like hypertension, diabetes mellites, bronchial asthma, history of allergy, hepatic and renal dysfunction. • Pregnant or lactating women • Patients on medication known to interact with neuromuscular blocking drugs e.g • Antibiotics (aminoglycosides and tetracycline), • Antidepressants (Lithium) • Anticonvulsants (Phenytoin, Carbamazepine) • Antiarrhythmics (calcium channel blockers like verapamil and nifedipine; and quinidine) • Magnesium sulphate

Design outcomes

Primary

MeasureTime frame
Time of onset Intubating conditions Duration of action of loading dose Total drug required Reversal characteristics Timepoint: 7 months

Secondary

MeasureTime frame
ï?? Hemodynamic effects ï?? Intra-operative and post-operative complications /side effects Timepoint: 7 months

Countries

India

Contacts

Public ContactDr Swati Bhatt

Government medical college,Baroda

drswatibhatt2015@yahoo.com9879372038

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026