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Effect of intravenous dexamethasone on the pain reducing ability of single sided ultrasound guided quadratus lumborum block in laparoscopic kidney surgeries

Effect of intravenous dexamethasone on the analgesic efficacy of unilateral ultrasound guided transmuscular quadratus lumborum block in laparoscopic renal surgeries: a double blind randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/034651
Enrollment
80
Registered
2021-07-07
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N289- Disorder of kidney and ureter, unspecified

Interventions

Intervention1: Pre induction QLB3 block with Post induction IV Dexamethasone: Patients will be given IV Dexamethasone 0.2 mg/kg after induction of anaesthesia Control Intervention1: Pre induction QLB3

Sponsors

Vimi Rewari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA Physical status of I - III 2. Age between 18-70 3. Patients undergoing elective laparoscopic renal surgeries

Exclusion criteria

Exclusion criteria: 1. Chronic analgesic use 2. Patients unable to communicate or operate a PCA pump 3. Contraindications to a regional anaesthetic technique 4. Allergy to local anaesthetics 5. BMI >35 6. Diabetic mellitus 7. Patient refusal or no informed consent or both

Design outcomes

Primary

MeasureTime frame
Total fentanyl consumption in the first 24 hours postoperatively as delivered by a PCA (Patient Controlled Analgesia) pumpTimepoint: 24 hours postoperatively—

Secondary

MeasureTime frame
Total intraop fentanyl requirement Time to activation of IV Fentanyl PCA pump postoperatively Postoperative pain at rest and on coughing as assessed by NRS at 30mins, 1hr, 2hrs, 4hrs, 8hrs, 12hrs and 24hrs postoperatively Incidence and severity of opioid - related adverse effects Requirement and dose of rescue analgesia Time to mobilisation to chair from T0(Time of arrival to PACU) Subjective sleep quality on the night of surgery QoR-40 score at 24 and 48 hrs postoperatively Timepoint: 30mins, 1hour, 2 hours, 4 hours, 8 hours, 12 hours, 24 hours and 48 hours postoperatively—

Countries

India

Contacts

Public ContactThota Geetha Supriya

All India Institute of Medical Sciences

vimirewari@gmail.com9818304880

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026