Health Condition 1: O100- Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
Conditions
Interventions
Intervention1: aspirin 75 mg versus aspirin 150 mg: above doses will be given in antenatal patients and maternal outcome will be analysed
Control Intervention1: Aspirin different dose: Aspirin 75mg ve
Sponsors
Balram pandit
Eligibility
Inclusion criteria
Inclusion criteria: �Previous history of preeclampsia �nulliparity �short( �h/o ART �family h/o chronic hypertension. �Obesity (BMI >29.9) �comorbidities like SLE, chronic hypertension, APS, kidney disease, DM
Exclusion criteria
Exclusion criteria: 1.allergic to aspirin and aspirin is contra indicated for medical reasons 2.refusal for consent 3.significant fetal malformations or presence of aneuploidy 4.low platelet count 5. patient on anticoagulation 6. patient already on aspirin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1 Incidence of preterm preeclampsia in both groups. 2 Complications of preeclampsia like HELLP, Eclampsia, acute kidney injury and postpartum eclampsia Timepoint: 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| .Incidence of antepartum and postpartum hemorrhage Gestation at delivery, mode of delivery. Need for blood transfusion and hospitalization for maternal or fetal indication. Development of IUGR, IUFD, fetal distress, neonatal death. Hemorrhagic disease of new born, respiratory distress in the newborn APGAR score, duration of NICU stay of the baby Timepoint: 1 YEAR | — |
Countries
India
Contacts
Public ContactDr SC saha
PGIMER chandigarh
Outcome results
None listed