Health Condition 1: - Health Condition 2: L811- Chloasma
Conditions
Interventions
Intervention1: Platelet rich plasma: In 30 patients after applying a layer platelet rich plasma on one half of face microneedling with needle length 1mm will be performed at 0, 3 and 6 weeks.
Control
Sponsors
Department of Dermatology Government Medical College and Hospital Sector B Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with clinical diagnosis of melasma (bilaterally symmetrical distribution). 2.Patients above the age of 18 years and below the age of 50 years.
Exclusion criteria
Exclusion criteria: 1.Patients with a history of bleeding disorders 2.Patients with hemoglobin level 3.Patients with local inflammatory skin disorders at the site of the procedure. 4.Patients with use of systemic corticosteroids within 2 weeks or corticosteroid injection application within 1 month at the site of procedure. 5.Patient with known hypersensitivity to platelet rich plasma or any other form of blood components and to tranexamic acid. 6.Patients with any other facial dermatoses. 7.Patients on anticoagulants, oral contraceptive pills 8.Patients using photosensitizing an use of other depigmenting oral or topical agents. 9.Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the comparative efficacy of platelet rich plasma therapy and tranexamic acid with microneedling in melasma.Timepoint: 0,3,6,9 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess adverse effects of platelet rich plasma and tranexamic acid with microneedling in melasma.Timepoint: 0,3,6,9 weeks | — |
Countries
India
Contacts
Public ContactDr Geeta Sharma
Government Medical College and Hospital, Chandigarh
Outcome results
None listed