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COMPARISON OF ULTRASOUND GUIDED ERECTOR SPINAE PLANE BLOCK (PAIN RELIEF TECHNIQUE) PERFORMED WITH DIFFERENT CONCENTRATIONS OF MEDICINE (BUPIVACAINE) FOR POST SURGERY PAIN SEVERITY, SURGICAL STRESS AND SATISFACTION IN PATIENTS UNDERGOING GALL BLADDER REMOVAL (LAPAROSCOPIC CHOLECYSTECTOMY) SURGERY.

COMPARISON OF THE EFFICACY OF ULTRASOUNDâ??GUIDED ERECTOR SPINAE PLANE BLOCK PERFORMED WITH DIFFERENT CONCENTRATIONS OF BUPIVACAINE FOR POSTOPERATIVE ANALGESIA, REDUCTION IN PERIOPERATIVE STRESS MARKERS AND PATIENT SATISFACTION IN LAPAROSCOPIC CHOLECYSTECTOMY PATIENTS : A PROSPECTIVE, RANDOMIZED, DOUBLE BLIND, CONTROLLED CLINICAL TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/034629
Enrollment
90
Registered
2021-07-06
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: Group 2 - USG - ESPB with 0.25% bupivacaine: USG Guided Erector spinae plane block given at the level of T7, with 20 ml of 0.25% bupivacaine bilaterally. Intervention2: Group 3 - USG -

Sponsors

Dr Ali Saloda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients aged 18-65yrs, posted for elective laparoscopic cholecystectomy, with American society of Anaesthesiologist (ASA) physical status I-II shall be included in the study.

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. Patients with known allergy to local anaesthetics. 3. Patients with presence of bleeding disorders. 4. Patients with infection at injection sites. 5. Patients with prior addiction or analgesics abuse (opioid and nonsteroidal anti-inflammatory drug medications). 6. Patients with BMI 34.9kg/m2. 7. Patients with weight under 50kgs. 8. Patients with liver or renal insufficiency. 9. Patients with history of psychiatric or neurological disease, deafness. 10. Patients in whom the total surgical duration exceeds 2 hours (after incision) or surgery is converted to open cholecystectomy.

Design outcomes

Primary

MeasureTime frame
To compare the reduction in Numerical Rating Scale (NRS) score at 30 minutes after extubation between the control group, group receiving ESPB with bupivacaine 0.25% and the group receiving ESPB with bupivacaine 0.375% respectively.Timepoint: 30 minutes after extubation—

Secondary

MeasureTime frame
1. To compare total intraoperative fentanyl requirement in the 3 groups. 2. To compare total analgesic consumption postoperatively in 24 hours between the 3 groups. 3. To compare change in pre and post-operative surgical stress markers (NLR- neutrophil-lymphocyte ratio, PLR- platelet-lymphocyte ratio, Serum albumin, Blood glucose) between the 3 groups. 4. To compare patient satisfaction scores between the three groups. Timepoint: 24 hours after extubation. For stress markers- 6 hours and 24 hours after extubation—

Countries

India

Contacts

Public ContactDr ALI SALODA

HAMDARD INSTITUTE OF MEDICAL SCIENCES AND RESEARCH

hod.anaesthesia@himsr.co.in9622457554

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026