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Differential severity of COVID-19 outcomes between Indians in India and the UK

Explaining the differential severity of COVID-19 between Indians in India and the UK - DiSeCT

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/07/034623
Enrollment
100800
Registered
2021-07-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: NONE: NONE

Sponsors

Indian Institute of Public Health Bangalore Public Health Foundation of India
Lead Sponsor
ICMR National Institute of Nutrition
Collaborator
Indian Institute of Public Health Hyderabad Public Health Foundation of India
Collaborator
London School of Hygiene and Tropical Medicine
Collaborator
National Institute of Mental Health and Neuro Sciences
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Participants from the MAASTHI and APCAPS cohort. 2. COVID-19 positive diagnosed patients willing and able to give informed consent. 3. In case of death, next of kin willing to participate

Exclusion criteria

Exclusion criteria: 1. Participants below 18 years 2. No informed consent

Design outcomes

Primary

MeasureTime frame
Differences in severity rates of COVID-19 between Indian populations in India compared to UK: 1. in age-sex composition and epidemiological curve 2. by burden of obesity, cardio-metabolic conditions or respiratory conditions 3. by cross-immunity acquired from exposure to other coronaviruses or immunity acquired from tuberculosis, BCG vaccination, malaria 4. Determine biological mechanisms linking severe COVID-19 to obesity, cardio-metabolic disease, respiratory conditions, immunity? Timepoint: 1.Every two months 2. Post hospitalization or death—

Secondary

MeasureTime frame
Differences in severity rates of COVID-19 between Indian populations in India compared to UK: 1. in age-sex composition and epidemiological curve 2. by burden of obesity, cardio-metabolic conditions or respiratory conditions 3. by cross-immunity acquired from exposure to other coronaviruses or immunity acquired from tuberculosis, BCG vaccination, malaria 4. Determine biological mechanisms linking severe COVID-19 to obesity, cardio-metabolic disease, respiratory conditions, immunity? Timepoint: 1.Every two months 2. Post hospitalization or death—

Countries

India, United Kingdom

Contacts

Public ContactDr Giridhara Rathnaiah Babu

Indian Institute of Public Health, Bangalore - Public Health Foundation of India

giridhar@iiphh.org9845036197

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026