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Normal Saline Nasal Wash and Gargle for COVID-19

Effect of Normal Saline Nasal Spray and Gargle (NSNSG) on oxygen dependent COVID-19 patients. - NSNSG

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/034605
Enrollment
150
Registered
2021-07-05
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere Health Condition 2: J09X- Influenza due to identified novelinfluenza A virus Health Condition 3: J22- Unspecified acute lower respiratory infection

Interventions

Intervention1: Normal Saline Nasal Spray and Gargle: Procedures to be done: a. Normal Saline Nasal Spray and Gargle (NSNSG) for one minute per nostril
till the saline water comes out through opposite nostril and gargle with saline water for one minute would be started as early as admission along with monitoring of oxygen inhalation. b. NSNSG three
they would be treated with conventional treatment protocol. However, biochemical tests and HRCT chest would be done on admission and after five days, similar to intervention group.

Sponsors

Department of Health and Family WelfareGovernment of West Bengal India
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. People aged more than 18 years irrespective of gender. 2. Sp02 level below 90% on admission, however can perform NSNSG produre.

Exclusion criteria

Exclusion criteria: 1. In ability / refuse to do the procedure. 2. Patient having SpO2 level below 90% but clinically unstable and/or disoriented. 3. Patient on high flow nasal cannula (HFNC) or other more invasive method.

Design outcomes

Primary

MeasureTime frame
A.Diminution of oxygen requirement. B.Improvement in severity score in HRCT lung compared to control group. Timepoint: 5-6days

Secondary

MeasureTime frame
A. Biochemical improvements of Cytokine markers in COVID-19. B. Reduction of Hospital Stay. C. Clinical improvement (composite markers, we may use COVID Patient Management System (CPMS) score sheet. Timepoint: 5-6 days

Countries

India

Contacts

Public ContactUDAY SANKAR CHATTERJEE

PARK MEDICAL RESEARCH AND WELFARE SOCIETY

udaysankarchatterjee@yahoo.com9831017686

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026