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A study to compare the effect of Dexmedetomidine and Lignocaine in attenuating haemodynamic response to laryngoscopy and endotracheal intubation

Attenuation of Haemodynamic response to Laryngoscopy and Endotracheal intubation with intravenous Dexmedetomidine and intravenous Lignocaine : A Comparative study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/034519
Enrollment
64
Registered
2021-07-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Intravenous Dexmedetomidine: 0.75 mcg/kg of Dexmedetomidine IV given 5 minutes prior to induction with 2mg/kg Propofol Control Intervention1: Intravenous Lignocaine: 1.5mg/kg of Lignoca

Sponsors

Ruth Lalnuntawmpuii
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I and II and patients posted for elective surgery who has given consent

Exclusion criteria

Exclusion criteria: 1. ASA grade III and IV 2. Uncontrolled hypertension, diabetes, cardiac, renal, hepatic, cerebral and peripheral vascular diseases 3. Bradycardia 4. Morbid obesity 5. History of allergy to study drugs 6. Patients in whom intubation attempts lasted longer than 15 seconds 7. Patients with anticipated difficult airway

Design outcomes

Primary

MeasureTime frame
Haemodynamic response to laryngoscopy and endotracheal intubationTimepoint: Haemodynamic response to laryngoscopy and endotracheal intubation duting intubation, 1 minute, 2 minutes, 3 minutes and 5 minutes after intubation—

Secondary

MeasureTime frame
NilTimepoint: Nil—

Countries

India

Contacts

Public ContactDr Longjam Eshori

Regional Institute of Medical Sciences, Imphal

drlongjam@gmail.com9436036407

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026