Health Condition 1: G968- Other specified disorders of central nervous system
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Clinical diagnosis of PNES confirmed by home video and a similar episode induced in video-EEG with no ictal correlates
Exclusion criteria
Exclusion criteria: i) A coexistent diagnosis of epilepsy (past/current) ii) Current drug/alcohol dependence iii) Patients with episode frequency iv) Patients with coexisting non-neurologic comorbidities like chronic cardiac, renal and other systemic diseases v)Patients not giving consent vi) Patients with intellectual disability vii) Patients with acute psychosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in monthly episode frequency, measured at baseline and the end of study- i.e. 6 monthsTimepoint: Reduction in monthly episode frequency, measured at baseline and the end of study- i.e. 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| i) Duration of freedom from episodes ii) Change in quality of life, measured by QOLIE-31 iii) Reduction in use of anti-seizure drugs iv) Improvement in psychological comorbidities, measured by HAMA and HAMD scales at baseline and end of 6 months v) Change in WSAS scale at follow up Timepoint: Baseline and after 6 months | — |
Countries
India
Contacts
AIIMS, Delhi