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ASSESSMENT OF DEVELOPMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA

LIVER STIFFNESS MEASUREMENT USING TRANSIENT ELASTOGRAPHY IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/06/034461
Enrollment
97
Registered
2021-06-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G473- Sleep apnea

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

ALL INDIA INSTITUTE OF MEDICAL SCIENCES RISHIKESH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age > 18 years. 2. Diagnosis of OSA based on International Classification of Sleep Disorders (ICSD) â?? 3 criteria: ï?· Diagnosis requires (A+B) or C: A. The presence of one or more of the following: 1.The patient complains of sleepiness, nonrestorative sleep, fatigue, or insomnia symptoms. 2.The patient wakes with breath holding, gasping, or choking. 3.The bed partner or other observer reports habitual snoring, breathing interruptions, or both during the patientâ??s sleep. 4.The patient has been diagnosed with hypertension, a mood disorder, cognitive dysfunction, coronary artery disease, stroke, congestive heart failure, atrial fibrillation, or type 2 diabetes mellitus. B. Polysomnography (PSG) or OCST demonstrates: Five or more predominantly obstructive respiratory events (obstructive and mixed apneas, hypopneas, or respiratory effort related arousals [RERAs]) per hour of sleep during a PSG or per hour of monitoring (OCST). C. PSG or OCST demonstrates: Fifteen or more predominantly obstructive respiratory events (apneas, hypopneas, or RERAs) per hour of sleep during a PSG or per hour of monitoring (OCST). 3. Non-alcoholic individuals or individuals who consume less than 20 g of alcohol per day. History will be confirmed by two family members.

Exclusion criteria

Exclusion criteria: 1.Age 2.Causes of Chronic liver disease other than NAFLD 3.Patients with secondary causes of NAFLD such as drugs, jejunoileal bypass or extensive small bowel resection or total parenteral nutrition. 4. Patients who do not give consent

Design outcomes

Primary

MeasureTime frame
1. LIVER STIFFNESS MEASUREMENT 2. CONTROLLED ATTENUATION PARAMETERTimepoint: AT TIME OF DIAGNOSIS OF OBSTRUCTIVE SLEEP APNEA—

Secondary

MeasureTime frame
1. HEMOGRAM 2. SERUM LIPID PROFILE 3. HOMA-IRTimepoint: AT TIME OF DIAGNOSIS OF OBSTRUCTIVE SLEEP APNEA—

Countries

India

Contacts

Public ContactROHIT GUPTA

ALL INDIA INSTITUTE OF MEDICAL SCIENCES, RISHIKESH

docgupta1976@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026