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Effect of blood pressure on eye pressure, retina, field of vision and blood flow of the eye

Effect of hypertension on intraocular pressure, retinal nerve fibre layer thickness, visual fields and ocular blood flow

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/06/034460
Enrollment
228
Registered
2021-06-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I10- Essential (primary) hypertension

Interventions

None listed

Sponsors

JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Group 1: Inclusion Criteria 1. Hypertensive patients on drug therapy for > 1 year. 2. Age > 18 years. Group 2: Inclusion Criteria Patients/persons without hypertension (BP Age >18 years

Exclusion criteria

Exclusion criteria: Group 1 and 2: Exclusion Criteria 1. Patients with BCVA worse than 20/40 or IOP >=22mmHg, at initial evaluation. 2. Known patients of glaucoma or with a history of glaucoma therapy (medical, laser, or surgical). 3. Patients with any ophthalmic disorders that preclude RNFL/macular evaluation and visual field testing viz. corneal opacities, dense cataract, retinal diseases (diabetic retinopathy, vascular occlusions, ARMD, degenerations/dystrophies). 4. Patients with chronic kidney disease or any nephropathy. 5. Patients with hypertensive emergencies.

Design outcomes

Primary

MeasureTime frame
1. To correlate IOP, RNFL thickness and visual field with blood pressure and perfusion parameters (SBP, DBP, MAP, MOPP). 2. To correlate ocular blood flow velocities and CMIT with blood pressure and perfusion parameters (SBP, DBP, MAP, MOPP)Timepoint: Day 1

Secondary

MeasureTime frame
To correlate IOP, RNFL thickness, visual field, ocular blood flow and CMIT with duration and severity (resistant hypertension, drug usage) of hypertension.Timepoint: Day 1

Countries

India

Contacts

Public ContactDr Geeta Behera

Jawaharlal Instiute of Postgraduate Medical Education and Research (JIPMER)

geeta.anandaraja@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026