Health Condition 1: N19- Unspecified kidney failure
Conditions
Interventions
Intervention1: Not giving saline flush: In no-saline or saline-free arm, hemodialysis will be conducted without intermittent saline flushes
Control Intervention1: Intermittent saline flush strategy: I
Sponsors
Department of Nephrology PostGraduate Institute Of Medical Education and Research Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: All patients with renal dysfunction due to any etiology who have been prescribed heparin-free hemodialysis from a nephrologist will be considered eligible for this study if they are above 18 years of age and satisfy ANY of the following criteria 1) Patients suffering from thrombocytopenia (Platelet 2) Patients with coagulopathy with either INR > 2 or aPTT > 40 seconds. 3) Patients with evidence of acute or active bleeding from any site. 4) Patients suffering from any bleeding diathesis. 5) Patients receiving any form of systemic anticoagulation in therapeutic doses.
Exclusion criteria
Exclusion criteria: Patients who meet ANY of the following criteria will be excluded: 1)Patients unable to attain and tolerate hemodialysis at blood flow >= 250ml/min. 2)Patient planned to receive blood products during hemodialysis. 3)Patients suffering from a known thrombophilic state. 4)Patient unwilling to give written informed consent to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clotting of extracorporeal circuit more than or equal to grade 3 clottingTimepoint: Within 4 hours of dialysis | — |
Secondary
| Measure | Time frame |
|---|---|
| Fraction of dialyzerâ??s fibre bundle volume lossTimepoint: Within 4 hours of dialysis | — |
Countries
India
Contacts
Public ContactDr Shubham Shukla
Postgraduate Institute of Medical Education and Research
Outcome results
None listed