"Comparison of recovery of mental and motor skills in patients receving either intravenous propofol or dexmedetomidine infusions as part of balanced general anaesthesia:A prospective randomized single-blind study"

"Comparison of psychomotor recovery in patients receiving either intravenous propofol or dexmedetomidine infusions as part of balanced general anaesthesia: A prospective randomized single-blind study"

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/06/034393

Enrollment

Registered

2021-06-25

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Comparison of psychomotor recovery in patients receiving either intravenous propofol or dexmedetomidine infusions as part of balanced general anaesthesia: Group Dexmedetomidine(Group D)

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with American Society of Anaesthesiologists physical status I, II, III aged 18 to 65 years. 2.Patients who are scheduled for surgeries under general anaesthesia. 3.Minimum duration of surgery lasting more than 120 minutes.

Exclusion criteria

Exclusion criteria: 1.Patients unwilling to participate in the study. 2.Patients who are unable to give informed consent. 3.BMI >30kg/m2. 4.Patients with known history of psychiatric illness, chronic drug or alcohol abuse. 5.Patients with known hypersensitivity to drugs used. 6.Pregnant and lactating women. Patients on concurrent sedative medications. 7.Patients who are unable to attempt or perform the DSST test.

Design outcomes

Primary

Measure	Time frame
compare the psychomotor recovery of patients receiving iv dexmedetomidine versus iv propofol infusion with Digit Symbol Substitution Test(DSST)[Annexure1] postoperativelyTimepoint: 15 min, 30 min , 60 min , 90 min , 120 min	—

Secondary

Measure	Time frame
i.To note the number of additional bolus doses of fentanyl and propofol given intraoperatively. ii.To note the total amount of propofol and fentanyl consumed intraoperatively. iii.To compare the time taken from stoppage of infusion to opening of eyes before administration of reversal agent. iv. To assess the sedation of patients with Ramsay Sedation Assessment Scale. Timepoint: 15 min, 30 min, 60 min , 90 min, 120 min	—

Measure

Time frame

i.To note the number of additional bolus doses of fentanyl and propofol given intraoperatively. ii.To note the total amount of propofol and fentanyl consumed intraoperatively. iii.To compare the time taken from stoppage of infusion to opening of eyes before administration of reversal agent. iv. To assess the sedation of patients with Ramsay Sedation Assessment Scale. Timepoint: 15 min, 30 min, 60 min , 90 min, 120 min

—

Countries

India

Contacts

Public ContactDrNHemanth

Sri Venkateswara Institute of Medical Sciences

hemanthn1973@gmail.com9440285634

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026