FindTrial
Sign In

To study the effectiveness of Fentanyl-Ketamine-Magnesium drug combination in the management of pain following open chest surgery , when injected into the veins by means of an electronic device which functions on patient demand

Fentanyl-Ketamine-Magnesium multimodal PCA vs. Morphine PCA for managing acute post thoracotomy pain, an institutional randomized control study

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/06/034347
Enrollment
50
Registered
2021-06-23
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J852- Abscess of lung without pneumonia Health Condition 2: J479- Bronchiectasis, uncomplicated Health Condition 3: C349- Malignant neoplasm of unspecifiedpart of bronchus or lung Health Condition 4: O- Medical and Surgical

Interventions

Intervention1: Patient controlled analgesia with a combination of Fentanyl, Ketamine and Magnesium.: All the patients undergoing thoracotomy, who fall under the inclusion criteria will be recruited fo

Sponsors

CMC Vellore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a. Inclusion Criteria: ââ??? Patients undergoing thoracotomy ââ??? Age 18 ââ?¬â?? 60 ââ??? ASA 1 and 2 ââ??? Creatinine Clearance >50ml/min

Exclusion criteria

Exclusion criteria: b. Exclusion Criteria: ââ??? ASA 3 and above ââ??? Age 60 ââ??? Allergy to drugs used ââ??? Hypermagnesemia ââ??? Previous chronic opioid use ââ??? Inability to use PCA pump

Design outcomes

Primary

MeasureTime frame
Post operative pain scores ââ?¬â?? VAS and NRSTimepoint: 0,6,12,24, 36 and 48 hours after surgery—

Secondary

MeasureTime frame
1. Number of doses attempted/delivered in PCA 2. Total opioid use 3. Ramsay Sedation Score 4. Nausea 5. Vomiting 6. Constipation 7. Urinary retention 8. Itching 9. Intervention for urinary retention (Catheter, nursing methods) 10. Quality of sleep 11. Patient satisfaction Timepoint: 0,6,12,24, 36 and 48 hours after surgery—

Countries

India

Contacts

Public ContactNitish Vijayanand

CMC Vellore

drsathish78@yahoo.com6369379259

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026