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Is Tab Ivermectin and Cap Doxycycline taken before Inj Remdesivir helping in reducing mortality in severe Covid 19 patients?

Comparison of efficacy of Ivermectin and Doxycycline with Remdesivir versus Remdesivir in severe covid 19 cases ââ?¬â?? A Retrospective analysis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/06/034344
Enrollment
150
Registered
2021-06-23
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere

Interventions

None listed

Sponsors

Rajarajeshwari Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients aged > 18 years 2.Either Sex 3.Confirmed cases of Covid-19 by RT-PCR 4.Patients able to take oral drug. 5.Patients requiring NIV or NRBM for maintaining saturation 6. Patients who have started with Tab Ivermectin and Cap Doxycycline before admission to ICU 7. Patients who have completed the Tab Ivermectin 12mg OD for 3 days and Cap Doxycycline 100mg BD for 5 days before admission in ICU

Exclusion criteria

Exclusion criteria: 1.Patients 2. Patients with drowsy on admission to ICU 3. Patients who are drowsy and not able to take orally 4.Patients who did not complete the Tab Ivermectin and Cap Doxycycline as per protocol 5.Patients with Liver diseases. 6.Patients with ischaemic heart disease. 7.Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
To determine whether Tab Ivermectin and Tab Doxycycline started before Inj Remdesivir was associated with lower mortality rate in patients hospitalized with COVID-19 compared to patients treated with Inj Remdesivir only along with other standard treatment regimen.Timepoint: Followup at 14 days after discharge from ICU

Secondary

MeasureTime frame
Total duration of ICU stay in both the groups.Timepoint: 14 days after admission to ICU

Countries

India

Contacts

Public ContactJyoti Petkar

Rajarajeshwari Medical College and Hospital, Bangalore, state- Karnataka

jokiran2009@gmail.com07726899533

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026