Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients aged > 18 years 2.Either Sex 3.Confirmed cases of Covid-19 by RT-PCR 4.Patients able to take oral drug. 5.Patients requiring NIV or NRBM for maintaining saturation 6. Patients who have started with Tab Ivermectin and Cap Doxycycline before admission to ICU 7. Patients who have completed the Tab Ivermectin 12mg OD for 3 days and Cap Doxycycline 100mg BD for 5 days before admission in ICU
Exclusion criteria
Exclusion criteria: 1.Patients 2. Patients with drowsy on admission to ICU 3. Patients who are drowsy and not able to take orally 4.Patients who did not complete the Tab Ivermectin and Cap Doxycycline as per protocol 5.Patients with Liver diseases. 6.Patients with ischaemic heart disease. 7.Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine whether Tab Ivermectin and Tab Doxycycline started before Inj Remdesivir was associated with lower mortality rate in patients hospitalized with COVID-19 compared to patients treated with Inj Remdesivir only along with other standard treatment regimen.Timepoint: Followup at 14 days after discharge from ICU | — |
Secondary
| Measure | Time frame |
|---|---|
| Total duration of ICU stay in both the groups.Timepoint: 14 days after admission to ICU | — |
Countries
India
Contacts
Rajarajeshwari Medical College and Hospital, Bangalore, state- Karnataka