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use of NT-pro BNP to detect kidney failure after liver transplantation

Perioperative N-terminal pro B-type natriuretic peptide (NT-proBNP) as a diagnostic screening tool for development of early post transplant AKI after Living Donor Liver Transplantation(LDLT) : A prospective cohort study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/06/034332
Enrollment
70
Registered
2021-06-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K721- Chronic hepatic failure

Interventions

None listed

Sponsors

Institute of liver and biliary sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients (18-65 years) with decompensated cirrhosis undergoing living donor liver transplant at Institute of Liver and Biliary Sciences.

Exclusion criteria

Exclusion criteria: Patient refusal. Paediatric patients. Patients with severe cardiac disease. [EF 1:3), Atrial Fibrillation with rapid ventricular response ( >100 beats/min)]. Acute liver failure. Patients with recent H/o AKI (

Design outcomes

Primary

MeasureTime frame
Assess the ability of NT-pro-BNP to predict early AKI after LDLTTimepoint: upto 7 days post liver transplant—

Secondary

MeasureTime frame
To assess the relationship between perioperative NT-proBNP level with postoperative morbidity (duration of mechanical ventilation, ICU and hospital length of stay, cardiac events). 2. Correlation of perioperative NT-ProBNP with cirrhotic cardiomyopathy and postoperative cardiac dysfunction. 3. Comparison of NT-ProBNP with established markers of AKI (serum cystatin C and urine NGAL). Timepoint: Baseline, 24 hours after surgery, preop 2d echo (within 3 months) and post transplant 2d echo within 7 days.—

Countries

India

Contacts

Public Contactdheapak v

institute of liver and biliary sciences

lgmitra@hotmail.com997192343

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026