None listed
Conditions
Interventions
Intervention1: Leukoreduction of Packed red blood cells by leukofiltration: The Packed red blood cells prepared from whole blood collected from healthy volunteers will be leukoreduced by leukofiltrati
Sponsors
Institute of Liver and Biliary Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. PRBC units prepared from whole blood units collected as per donor eligibility criteria laid by drugs and cosmetics act as a part of quality control. 2. PRBC units leukoreduced by leukofiltration only. 3. PRBC units leukoreduced by buffy coat removal followed by leukofiltration.
Exclusion criteria
Exclusion criteria: 1. Transfusion Transmitted Infections reactive ( HIV Ag/Ab, HBsAg, anti HCV, Malarial Parasite, VDRL ) whole blood units. 2. Whole blood units failing routine quality control inspection like under collected, over collected, hemolyzed and lipemic units.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Residual leukocyte count per unit will be assessed in the packed red blood cells unitTimepoint: 1. Baseline leukocyte count will be assessed after collection of whole blood. 2. Residual leukocyte count per unit after leukoreduction of the packed red blood cells. 3. Residual leukocyte count at 42 days of storage | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage hemolysis will be assessed in the leukoreduced packed red cells unit.Timepoint: 1. After leukoreduction at the time of processing of the packed red blood cells unit. 2. At 42 days of storage of packed red blood cells unit | — |
Countries
India
Contacts
Public ContactVasudha Nassa
Institute of Liver and Biliary Sciences
Outcome results
None listed