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Evaluation of serum haptoglobins levels and cell free hemoglobin as predictors of mortality in patients with perforation peritonitis

Evaluation of serum haptoglobin and cell free hemoglobin levels as predictors of mortality in patients with perforation peritonitis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/06/034313
Enrollment
85
Registered
2021-06-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K650- Generalized (acute) peritonitis

Interventions

None listed

Sponsors

Government medical college and hospital chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient willing for participation in the study. All patients presenting in emergency with perforation peritonitis on clinical examination and radiological investigations.

Exclusion criteria

Exclusion criteria: 1. Patients operated outside GMCH and later referred to the center. 2. Patients with other causes of hyperhaptoglobinemia (raised cell free hemoglobin with increased haptoglobin), i.e, previously diagnosed cases of hepatitis, amyloidosis, collagen diseases, lymphoma, leukemia, steroid use, aplastic anaemia, or nephrotic syndrome. 3. Patients with known history of congenital causes of haemolytic anaemia (AIHA, hereditary spherocytosis, sickle cell disease, thalassemia), and cirrhosis, which will lead to persistent decrease in serum haptoglobin levels.

Design outcomes

Primary

MeasureTime frame
serum haptoglobin and cell free hemoglobin levelsTimepoint: 1 month

Secondary

MeasureTime frame
combination of serum haptoglobins and cell free hemoglobins as predictors of mortality in patients with perforation peritonitisTimepoint: 1 month

Countries

India

Contacts

Public ContactRajat Upadhyay

Government medical college and hospital

Dr_simrandeep@yahoo.co.in7454896111

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026