Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Control Intervention1: Dexmedetomidine: Intravenous route dose will be 1mcg/kg diluted in 20ml normal saline over 20 minutes using an infusion pump.
Nebulized route dose will be 1mcg/kg diluted with s
Sponsors
Arindam Chatterjee
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anaesthesiologists(ASA) physical status I and II. Aged between 18 and 60 years. Undergoing elective surgery under general anaesthesia with endotracheal intubation.
Exclusion criteria
Exclusion criteria: Known allergy to Dexmedetomidine. ASA III and IV. Predicted difficult airway planned for awake intubation. Emergency surgeries. Pregnant patients. Patients on treatment with beta blockers or other rate control drugs, pacemakers. Patient refusal to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Haemodynamic parameters like heart rate,blood pressure and oxygen saturation.Timepoint: Baseline,1 minute,2 minute,3 minute,4 minute,5 minute,7 minute,10 minutes post intubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation Score using the Modified Observers Alertness/Sedation Scale. Dose sparing effect of Propofol.Timepoint: Sedation score will be assessed 3 minutes prior to induction. | — |
Countries
India
Contacts
Public ContactArindam Chatterjee
Kasturba Medical College,Manipal
Outcome results
None listed