Health Condition 1: - Health Condition 2: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Intervention1: Capsule Duloxetine 60mg: Capsule Duloxetine 60 mg Stat dose per orally, will be given 2 hours prior to laparoscopic cholecystectomy operation for better analgesia.Patient will be chosen
Sponsors
Sharda Hospital School of Medical Sciences Research
Eligibility
Inclusion criteria
Inclusion criteria: 1. All the elective cases of Laparoscopic Cholecystectomy of ASA I or II, scheduled for general anesthesia
Exclusion criteria
Exclusion criteria: 1. Patient refusal 2. Patients with any known history of cardiovascular diseases 3.Patients with known case of hepatic and renal disease 4.Patients with known history of substance abuse 5.A chronic opioid abuser( >3 months), being on chronic Gabapentin or Pregabalin( >3months) 6.Patients on antidepressant drugs and patients with psychiatric disorders 7.Anticipitated difficult airway on preoperative assessment 8.Patients converted to open cholecystectomy from laparoscopic cholecystectomy 9. Patients in whom drain placement has been done 10.BMI >30 11.Pregnant and lactating females 12.History of allergy to any of the drug to be administered
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the analgesic efficacy of duloxetine premedication on post operative analgesic requirement in laparoscopic cholecystectomies using VAS score(Visual Analogue Scale)Timepoint: 12 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| a) Total dose of first and second rescue analgesic (InjParacetamol&InjTramadol) consumption in post operative period. b) Ramsey Sedation Score in Preoperative & postoperative period c) Hemodynamic changes d) Demographic data e) Incidence of side effects (if any)Timepoint: 12 hours | — |
Countries
India
Contacts
Public ContactDr Ambhrin Saha
School of Medical Sciences & Research
Outcome results
None listed