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application of growth factors after deep cleaning in the type 2 diabetes mellitus patient having gum disease.

Clinical evaluation of the combined efficacy of scaling and root planing (SRP) and injectable platelet rich fibrin (i-PRF) in the non-surgical periodontal therapy of Stage III and Grade C periodontitis patients having Type 2 Diabetes mellitus. -A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/06/034280
Enrollment
26
Registered
2021-06-17
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: i-PRF: Scaling and Root planing + i-PRF Control Intervention1: Saline: Scaling and Root planing + Saline

Sponsors

Shunmuga Prasanth D
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Type 2 Diabetes mellitus subjects with the glycaemic status having HbA1c >= 7 2.Subjects on oral medication for the management of Diabetes mellitus. 3.Subject with moderate periodontal disease with the case definition, StageIII and Grade C periodontitis, according to EFP-AAP periodontal disease classification 2017. i.e., Moderate periodontal destruction is defined as sites having >= 5mm probing pocket depth with attachment loss. 4.Moderate periodontal destruction at least, in 2 interproximal sites in each mandibular quadrant. 5.Minimum presence of 4 permanent teeth per mandibular quadrant (excluding 3rd molars).

Exclusion criteria

Exclusion criteria: 1.Sites with pseudo pockets / advanced periodontal destruction with mobility and Grade IV furcation involvement 2.Periodontal therapy within last 6 months 3.Previous history of intake of antibiotics over last 6 months 4.Systemic condition / disease other than Type II DM, having influence on course and treatment outcomes of periodontal disease. 5.Screening for the infectious disease will be done and the subjects with infectious diseases will be excluded. 6.Individuals with known platelet disorders 7.Smokers

Design outcomes

Primary

MeasureTime frame
To evaluate the changes in the: Clinical attachment level (CAL) before and after therapy within and between the groups.Timepoint: Baseline 3Months 6Months—

Secondary

MeasureTime frame
To evaluate the changes in the 1.Probing pocket depth (PPD) 2.Plaque index (PI) 3.Sulcular Bleeding Index (SBI) before and after therapy within and between the groups.Timepoint: Baseline 3Months 6Months—

Countries

India

Contacts

Public ContactDr Shunmuga Prasanth D

SRM dental college

anupamamds@gmail.com9677065517

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026