To compare intravenous infusion of lignocaine and dexmedetomidine for pain relief after surgery in patients undergoing total laparoscopic hysterectomy surgery

Comparison of intravenous infusion of lignocaine versus dexmedetomidine for postoperative pain relief in patients undergoing total laparoscopic hysterectomy

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/06/034267

Enrollment

Registered

2021-06-16

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous infusion of lignocaine versus intravenous infusion of dexmedetomidine: Comparison of intravenous infusion of lignocaine versus dexmedetomidine for postoperative pain relief

Eligibility

Inclusion criteria

Inclusion criteria: Patients of age between 35-60 years belonging to ASA physical status I and II scheduled for elective total laparoscopic hysterectomy under general anaesthesia.

Exclusion criteria

Exclusion criteria: • Consent refusal. • Patients on anti-arrythmic drugs. • Patients with known history of coronary artery disease, liver disease. • Allergic to a local anesthetic. • Psychiatric patients. • Inability to comprehend VAS

Design outcomes

Primary

Measure	Time frame
1. Post-operative VAS score 2. Total opioid consumption in 24 hours Timepoint: 1. Post-operative VAS score 2. Total opioid consumption in 24 hours	—

Secondary

Measure	Time frame
1. Time of administration of first and subsequent rescue analgesic and number of times rescue analgesic needs to be given. 2. The adverse effects of the drugs such as nausea, vomiting, hypotension, sedation, bradycardia. Timepoint: 24 hours	—

Countries

India

Contacts

Public ContactDinesh Sood

Dayanand Medical College and Hospital, Ludhiana

drdineshsood@gmail.com9814020817

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026