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Comparison of two inhalational anaesthetic agents, sevoflurane and desflurane for giving anaesthesia

Comparison of sevoflurane with desflurane for volatile induction and maintenance anaesthesia (VIMA) in patients undergoing laparoscopic surgical procedures

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/06/034266
Enrollment
80
Registered
2021-06-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Volatile induction and maintenance anaesthesia: Comparison of volatile induction and maintenance anaesthesia using two inhalational agents viz : sevoflurane and desflurane Dose - Titrat

Sponsors

Adesh institute of medical sciences and research Bathinda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I, II Weight between 50 -90 kgs Non emergency surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: Age Patients with uncontrolled co-existing systemic or metabolic dieseases. However their controlled counterparts (considered as ASA II ), shall be considered History of alcohol or substance abuse Known sensitivity to sevoflurane , desflurane or an other halogenated anaesthetic agent Undergone recent GA within 7 days Potential susceptibility to malignant hyperthermia .

Design outcomes

Primary

MeasureTime frame
1. Intraoperative parameters such as heart rate, SPO2, ECG changes, 2. Blood pressure measurements (systolic, diastolic and mean arterial pressures) 3. Depth of anaesthesia monitoring using Conox device in which two main indices qCON and qNOX will be kept at predetermined level, which correlate to the patients level of consciousness and patients response to noxious stimuli respectively 4. The recovery of the patients ( Modified Aldrete Score ). Timepoint: T0 - time at which the will be patient shifted to O.T T1 - time from the onset of volatile agent inhalation to the loss of eyelash reflex T2 - time taken for intubation T3 - time at which the volatile agent will be stopped T4 â?? extubation time

Secondary

MeasureTime frame
1. To prevent, determine and treat the complication/side effects if any Timepoint: T0 - time at which the will be patient shifted to O.T T1 - time from the onset of volatile agent inhalation to the loss of eyelash reflex T2 - time taken for intubation T3 - time at which the volatile agent will be stopped T4 â?? extubation time

Countries

India

Contacts

Public ContactGurleen kaur randhawa

Adesh institute of Medical Sciences and Research, Bathinda

drmmprao1@gmail.com8699921884

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026