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Compare and study pain relieving effect of Dexamethasone, Cold saline (Cryotherapy) and Tramadol hydrochloride as a last irrigant on the after treatment Pain in Patients with Symptomatic Irreversible Pulpitis in Single Rooted Teeth. â??A Randomized Double- Blind Clinical Study.â??

Comparative Evaluation of Analgesic Efficacy of Dexamethasone, Cold saline (Cryotherapy) and Tramadol hydrochloride as a Final Irrigant on the Postoperative Pain in Patients with Symptomatic Irreversible Pulpitis in Single Rooted Teeth. â??A Randomized Double- Blind Clinical Study.â??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/06/034232
Enrollment
80
Registered
2021-06-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Normal saline: 1.To evaluate the analgesic efficacy of normal saline as a final irrigant on the postoperative pain in patients with symptomatic irreversible pulpits in single rooted tee

Sponsors

Unnati Sanjay Shah
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients between age group of 18-60 years with maxillary or mandibular single rooted teeth diagnosed with Symptomatic Irreversible Pulpitis with normal periapical tissues will be included in the study. 2. Teeth with radiographic findings revealing radiolucency in enamel, dentin involving pulp with no periapical changes will be included. 3. Patients with VAS score of 5 and above will be included. 4. A written informed consent will be taken from all the patients and only those patients ready to sign the consent form will be included in the study.

Exclusion criteria

Exclusion criteria: 1.Patients with severe or chronic apical periodontitis will be excluded 2.Teeth with periapical abscess, granuloma, cyst will be excluded. 3.Medically compromised patients will be excluded. 4.Teeth with open apex will be excluded. 5.Teeth with root resorption will be excluded. 6.Teeth with complex root canal anatomy will be excluded. 7.Pregnant and lactating women will be excluded. 8.Patients using medications such as analgesic or anti-in�ammatory drugs will be excluded. 9.Patients allergic to steroids and opioids will be excluded

Design outcomes

Primary

MeasureTime frame
1. To evaluate the analgesic efficacy of normal saline as a final irrigant on the postoperative pain in patients with symptomatic irreversible pulpits in single rooted teeth. 2. To evaluate the analgesic efficacy of dexamethasone as a final irrigant on the postoperative pain in patients with symptomatic irreversible pulpits in single rooted teeth. Timepoint: 6 hours and 12 hours and 24 hours

Secondary

MeasureTime frame
To compare and evaluate the analgesic efficacy of dexamethasone, cold saline(cryotherapy) and tramadol hydrochloride as a final irrigant on the postoperative pain in patients with irreversible pulpitis in single rooted teeth. Timepoint: 6hrs, 12hrs, 24hrs

Countries

India

Contacts

Public ContactUnnati Sanjay Shah

K M Shah Dental College and Hospital

drajayinendo@gmail.com8385017307

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026