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Significance and Relation of CGRP in Migraine Symptoms.

Study of Serum Calcitonin Gene Related Peptide (CGRP) in Migraine and its Correlation with Symptom Severity. - MICCO

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/06/034224
Enrollment
100
Registered
2021-06-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G439- Migraine, unspecified

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Dr Hafeeza Sultana
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients who are above 18 years and below 50 years of age, patients who are mobile, and patients who are consenting to participate in the study. 2) Patients with denovo (newly diagnosed) with Migraine and presenting with headache.

Exclusion criteria

Exclusion criteria: 1)Patients who are below 18 years and above 50 years of age, patients who are mobile, and patients who are consenting to participate in the study. 2)Patients who have conditions or co-morbidities like Myocardial Infarction, cardiac failure, Resistant Hypertension, Chronic Kidney Disease, Acute Kidney Failure- On Hemodialysis, Sepsis, and Temporomandibular Joint disorders because these conditions increase serum CGRP levels. 3)Patients having conditions which mimic Migraine like Intracranial Aneurysms, Space Occupying Lesion, Pituitary Adenomas, Exertional Headache, Crash Migraine and Cerebral Venous Thrombosis. 4)Pregnant or postmenopausal women were not included in the study as research has suggested that these conditions effect serum CGRP levels.

Design outcomes

Primary

MeasureTime frame
The primary outcome will be to measure serum CGRP levels in patients presenting with migraine and corelating it with symptom severity.Timepoint: One time point. Time 1 (T1): Patients serum CGRP levels are measured at baseline i.e., 0 weeks, and correlated with presenting symptoms.

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Hafeeza Sultana

Owaisi Hospital and Research Centre

hafeezasultana123@gmail.com7780620999

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026