Health Condition 1: 4- Measurement and Monitoring
Conditions
Interventions
Intervention1: Injection Dexmedetomidine intravenous: Injection Dexmedetomidine 0.5ug/kg diluted to 10ml normal saline administered intravenously over 10 minutes before induction.
Control Intervention
Sponsors
Yangchen Bhutia
Eligibility
Inclusion criteria
Inclusion criteria: Patients of either sex Patients with ASA physical grade I or II Patients with age group 18 to 60 years undergoing elective surgery under general anesthesia Patients willing to give written consent
Exclusion criteria
Exclusion criteria: Patients refusal Anticipated difficult airway (mallampati score >III, thyromental distance Patients with diabetes and hypertension Pregnant or breast feeding mother Patients with respiratory, cardiac,neurological,renal or liver diseases Patients with gastro-oesophageal reflux Patients with known allergy to drugs used for induction of anaesthesia Psychiatric patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare efficacy of dexmedetomidine and magnesium sulphate on the attenuation of stress response of laryngoscopy and intubation in patients undergoing general anaesthesia.Timepoint: Baseline Before intubation, just after intubation ,and also at 1,3,5,10 minutes after intubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare between dexmedetomidine and magnesium sulphate, a better drug for controlling the stress response.Timepoint: Baseline Before intubation, just after intubation, and also at 1,3,5,10 minutes after intubation | — |
Countries
India
Contacts
Public ContactDr Sanasam Sarat Singh
Regional Institute of Medical Sciences
Outcome results
None listed