Health Condition 1: M96-M96- Intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified
Conditions
Interventions
Intervention1: Tranexamic acid: 1 gram of injection tranexamic acid is given intravenously thirty minutes before skin incision
Intervention2: No treatment: No treatment
Sponsors
Kasturba medical college
Eligibility
Inclusion criteria
Inclusion criteria: 1. All open spine surgeries. 2. Patients with age 18 years and greater. 3. Patients with low risk of anaesthesia related complications( i.e. ASA I and ASA II patients ). will be enrolled for the study.
Exclusion criteria
Exclusion criteria: 1.Minimally invasive spine surgeries and unilateral single level fenestration discectomies. 2.Patients with age less than 18 years. 3.Patients with blood dyscrasias ,coagulation profile abnormality and renal disorders. 4.Patients with high risk of anaesthesia related complications ASA III and ASA IV patients. 5.Duration of surgery more than 6 hours. 6.Patients on medication which can interfere with tranexamic acid such as aspirin ,clopidogrel , dabigatran , heparin , enoxaparin , fondaparinux. will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Intraoperative blood loss in the group of patients receiving tranexamic acid and in the group of patients not receiving tranexamic acid. 2.Assessment of drop in 24 hour hemoglobin in the group of patients receiving tranexamic acid and in the group of patients not receiving tranexamic acid . 3.Assessment of postoperative drain output in the group of patients receiving tranexamic acid and in the group of patients not receiving tranexamic acid . Timepoint: one the day of surgery and upto 3 days postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| NATimepoint: NA | — |
Countries
India
Contacts
Public ContactDr Shyamasunder Bhat N
Kasturba Medical College, MAHE
Outcome results
None listed