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ASSOCIATION BETWEEN SINGLE NUCLEOTIDE POLYMORPHISM AND SERUM LEPTIN LEVELS IN PRE-ECLAMPSIA PATIENTS

ASSOCIATION OF NADH DEHYDROGENASE SUBUNIT 1 (ND1) GENE POLYMORPHISM AND SERUM LEPTIN LEVELS IN PRE-ECLAMPSIA PATIENTS.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/06/034168
Enrollment
150
Registered
2021-06-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O149- Unspecified pre-eclampsia

Interventions

None listed

Sponsors

Department of Biochemistry MAMC
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: INCLUSION CRITERIA: â??For cases : 1.Primigravida 2.Singleton pregnancy 3.Gestational age >30 weeks 4.New onset of hypertension having systolic BP >=140 mmHg and diastolic BP >=90 mmHg 5.Proteinuria >300mg/dl For control : 1.Primigravida 2.Age and gestational age matched subjects 3.Clinically normal and healthy pregnant subjects

Exclusion criteria

Exclusion criteria: Patients with chronic hypertension, coronary heart disease, kidney disorder, diabetes, thyroid disease or immunotherapy.

Design outcomes

Primary

MeasureTime frame
To establish an association between mtDNA mutations, preeclampsia and leptin.Timepoint: Baseline i.e. at the time of admission—

Secondary

MeasureTime frame
To understand role of mitochondria in pathophysiology of preeclampsia and its inheritance.Timepoint: Baseline i.e. at the time of admission—

Countries

India

Contacts

Public ContactDr Shailata Prisi

Maulana Azad Medical College

lchandra70@yahoo.com9873167313

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026