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Studying the clinical profile of PAH in infants, including their biochemical and genetic parameters

Clinical ,Biochemical And Genetic Profile Of Pulmonary Arterial Hypertension In Infants

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/06/034160
Enrollment
20
Registered
2021-06-10
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I288- Other diseases of pulmonary vessels

Interventions

None listed

Sponsors

Kasturba Medical College Manipal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Infants between 1 and 12 months of age, presenting with acute PAH in the Department of Paediatrics, KMC Manipal

Exclusion criteria

Exclusion criteria: A.Age 12 months B.PPHN C.Secondary causes of PAH, such as: a.Any disease associated with pulmonary causes of respiratory distress including bronchopneumonia, lower respiratory tract infections , bronchiolitis. b.Any Developmental anomaly of the lungs including Bronchopulmonary Dysplasia, Alveolar Capillary Dysplasia, Congenital Diaphragmatic Hernia, PAP, Pulmonary Hypoplasia. c.Any congenital heart disease d.Any known chronic systemic disease

Design outcomes

Primary

MeasureTime frame
Describe the clinical profile of presentation of PAH in infants between the ages of 1 and 12 months.Timepoint: Describe the clinical profile of presentation of PAH in infants between the ages of 1 and 12 months.

Secondary

MeasureTime frame
Identify the biochemical derangements present at onset of presentation. Identify the trends in Pulmonary Arterial pressures, from onset of symptoms to resolution of hypertension. To analyse the clinical outcome in terms of mortality, days spent in the ICU and hospital, resolution of symptoms based on the ongoing treatment protocol. Correlate the presence of PAH in infants to any dietary restrictions in their mothers.Timepoint: 1 year

Countries

India

Contacts

Public ContactDr Koushik H

Kasturba Medical College, Manipal

suneel.mundkur@manipal.edu9845150802

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026