Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intervention Arm: Intervention arm (Maintenance of central venous oxygen saturation of â?¥75%) Central venous oxygen saturation will be augmented by maintaining mean arterial pressur
Sponsors
Intramural FundingJIPMER
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age more than 60 years 2.American Society of Anesthesiologists (ASA) physical status I, II and III 3.Patient undergoing elective and emergency major abdominal surgery of any indication lasting more than two hours and/or expected blood loss >500 ml
Exclusion criteria
Exclusion criteria: 1. Patient already receiving mechanical ventilation 2.Patient already receiving inotrope 3.Poorly controlled hypertension 4 Contra indication to IJV catheterization 5. Planned reoperation within 3 months 6.Preoperative immobility or inability to walk unaided
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the effect of higher systemic oxygen delivery on composite of death, major postoperative complications compared to the standard careTimepoint: Post op day 1, day before discharge,After 3 month | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To assess the effect of increased systemic oxygen delivery on length of hospital stay compared to standard care 2. To assess the effect of increased systemic oxygen delivery on postoperative quality of life compared to standard care 3.To assess the effect of increased systemic oxygen delivery on cvs,rs,cns,renal and GIT system compared to standard care Timepoint: Post op day 1, day before discharge,After 3 month | — |
Countries
India
Contacts
Public ContactDr Ajay Kumar Jha
JIPMER
Outcome results
None listed