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A clinical trial to study the efficacy of induction of labour with Dinoprostone gel and Misprostol in term pregnancy.

Comparative study of induction of labour with intracervical Dinoprostone gel and Sublingual Misprostol.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/06/034104
Enrollment
100
Registered
2021-06-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80-O82- Encounter for delivery Health Condition 2: O610- Failed medical induction of labor

Interventions

Intervention1: dinoprostone gel: intracervical dinoprostone 0.5mg gel with sublingual misoprostol 25mcg in the induction of labour. Control Intervention1: Misoprostol: efficacy of labour with inductio

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: all pregnancies with singleton fetus with cephalic presentation over 37 weeks of gestation , with reactive fetal heart rate pattern and unfavourable cervix or unfavourable Bishops score with no contraindication for vaginal delivery

Exclusion criteria

Exclusion criteria: previous LSCS or any uterine surgery, malpresentations, grandmultiparity abnormal fetal heart rate patterns allergy to prostaglandins

Design outcomes

Primary

MeasureTime frame
assessment of mode of delivery, change in bishops score, time interval from induction to onset of adequate uterine contractions, need for augmentation of labour mode of delivery side effects neonatal outcomeTimepoint: 6 hours from induction of labour to onset of contractions

Secondary

MeasureTime frame
cost-effectiveness of labour induction and patient satisfactionTimepoint: 24 hours after delivery

Countries

India

Contacts

Public ContactDr Vandana Dave

Kasturba Hospital, Bhopal

cms_hr@bhel.in9425604776

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026