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To find out in woman sufferring with miscarriages if there exists a genetic cause in metabolism of a vitamin folic acid

Plasma Homocysteine levels correlated to Methylene Tetrahydro Folate Reductase gene mutation in women with unexplained Recurrent Pregnancy Loss/BOH at KIMS Hubli

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/06/034100
Enrollment
100
Registered
2021-06-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O039- Complete or unspecified spontaneous abortion without complication

Interventions

Intervention1: nil: nil Control Intervention1: nil: nil

Sponsors

Karnataka Institute Of Medical Sciences Hubli
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Women with more than or equal to two pregnancy losses (including 1st and 2nd trimester abortions, IUDs, still births) admitted at OR visiting KIMS, Hubli during the study period

Exclusion criteria

Exclusion criteria: Women with known etiology of recurrent pregnancy loss (Women with known gene defect, uncontrolled hormonal defect , APLA, anatomical uterine defects)

Design outcomes

Primary

MeasureTime frame
Expression of MTHFR gene in both the groups plasma values of Homocysteine levels in both the groupsTimepoint: baseline—

Secondary

MeasureTime frame
nilTimepoint: nil—

Countries

India

Contacts

Public ContactDr Sanjana Kumar

Karnataka Institute Of Medical Sciences Hubli

omkabadi@gmail.com9448210579

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026