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Comparison of two drugs on sore throat after intubation.

Comparison of dexmedetomidine nebulization and magnesium sulphate nebulization for post operative sore throat after general anaesthesia with endotracheal intubation

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/06/034027
Enrollment
100
Registered
2021-06-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nebulisation: Nebulisation with either dexmedetomidine or magnesium sulphate solution of 5 ml is done using face mask once 15 minutes prior to general anaesthesia in the pre operative h

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: i) Informed Written consent ii) Age between 18-65 years. iii) Patients undergoing surgery under general anesthesia. iv) ASA - 1 and ASA - II iv) Duration of surgery within 3 hrs

Exclusion criteria

Exclusion criteria: 1.Emergency surgeries 2.Patients undergoing Tonsil,thyroid and other throat surgeries. 3.Surgeries more than 3 hrs duration. 4.Allergy to study drugs â?? to prevent anaphylaxis 5.Patients on pain medication,Calcium channel blockers,Quinolones And tetracyclines. 6.Myasthenia Gravis and Heart blocks. 7.Chronic renal failure and pre existing myopathy

Design outcomes

Primary

MeasureTime frame
Comparing efficacy of Magnesium sulphate and Dexmedetomidine nebulization for postoperative sore throat after general anaesthesia with endotracheal intubationTimepoint: 0,2,4,8,16 and 24 hrs after general anaesthesia

Secondary

MeasureTime frame
To compare the side effects and adverse events of Magnesium Sulphate and Dexmedetomidine nebulization.Timepoint: 0,2,4,8,16 and 24 hrs after General anaesthesia.

Countries

India

Contacts

Public ContactK Shanthini

ESIC MC and Hospital Ethical committee

ganeshbabu.nandhini29@gmail.com7550238528

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026