Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: clinical periodontal parameters, salivary biomarker: Plaque index, Modified gingival index, Probing depth,Bleeding on probing, Recession, Loss of attachment will be measured using UNC 1
Sponsors
Haldia Institute of dental sciences and research
Eligibility
Inclusion criteria
Inclusion criteria: Subjects with Gingivitis : full mouth bleeding on probing less than 10% of sites. Subjects with Periodontitis : Subjects with Periodontitis with interdental clinical attachment loss detectable at >- 2 non adjacent teeth .Buccal or oral clinical attachment loss >-3 mm with pocketing > 3mm is detectable at >-2 teeth. Subjects with Periodontally Healthy (PH) : Subjects with PH will have no history of periodontitis, no sites with PD and CAL > 3 mm concurrently and no more than 10% of the sites with gingival bleeding and/or BoP. Diabetic subjects :The diabetic subjects will require a diagnosis of DM confirmed by a physician, dating from at least 2 years prior to the study. In addition, all diabetic patients will be required to have a HbA1c > 6.5% and FPG > 99 mg/dl. Non-diabetics: Non-diabetic subjects will have no history of DM, HbA1c = 6.0% and FPG
Exclusion criteria
Exclusion criteria: Pregnancy; breastfeeding; subgingival periodontal therapy during the previous 12 months; use of antibiotic, anti-inflammatory, and/or immunosuppressive therapies during the previous 6 months; regular use of mouthrinses containing antimicrobials; use of orthodontic appliances; presence of other infectious, immunological, and/or inflammatory systemic conditions (e.g., immunological disorders, rheumatoid arthritis) and major complications of DM (i.e.,ulcers, gangrene, amputation, neuropathy, and nephropathy),smokers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| changes in clinical periodontal status, salivary biomakers level and markers of diabetes controlTimepoint: at 3, 6 and 12 months after non surgical periodontal therapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Oral health behaviour and Quality of life assessmentTimepoint: 3,6 and 12 months | — |
Countries
India
Contacts
Public ContactSwet Nisha
Haldia Institute of Dental Sciences and Research,Division Of Dentistry,Department Of Periodontology
Outcome results
None listed