Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: pregabalin 150 mg oral tablet
clonidine200mcg oral tablet
melatonin6 mg oral tablet
: given 2hours before start of surgery with a sip of water and hemodynamic parameters studied mainly
Sponsors
Otherself
Eligibility
Inclusion criteria
Inclusion criteria: ASA grade I and II between the age group 20 years and 60 years of either sex with written informed consent will be randomly selected who are undergoing laproscopic abdominal surgeries under general anaesthesia.
Exclusion criteria
Exclusion criteria: Patient with preexisting cardiac disease Hypertension Asthma Severe renal or hepatic dysfunction Patients with anticipated difficult intubation Pregnancy Patient with known allergy to study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To access the efficacy of oral pregabalin, oral melatonin and oral clonidine on hemodynamic changes during laryngoscopy and intubationTimepoint: at 1 min, 3 min, 5 min., followed by every 10 min. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the effectiveness of test drugs in reducing pre operative anxiety and post operative pain.Timepoint: at 1 min, 3 min, 5 min., followed by every 10 min. | — |
Countries
India
Contacts
Public ContactVishakha Tanwar
Mahatma Gandhi University of Medical Science and Technology
Outcome results
None listed