Comparision of two methods of anaesthetic depth monitoring on recovery profile in desflurane based general anaesthesia in neurosurgical population .

Comparision of Patient State Index and End Tidal Anaesthetic Concentration monitoring on recovery profile in desflurane based anaesthesia in neurosurgical population.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/05/033897

Enrollment

108

Registered

2021-05-31

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Patient State Index monitoring for quantifying the level of hypnosis in the intraoperative period: Patient State Index (PSI) sensors will be applied to the forehead of the patient. The

Eligibility

Inclusion criteria

Inclusion criteria: Patients with ASA physical status 1 and 2 undergoing elective neurosurgeries lasting for more than 3 hours.

Exclusion criteria

Exclusion criteria: 1.Patients with history of psychiatric illness and patients in altered sensorium. 2.Patients with history of alcohol or drug abuse. 3.Patients with Body mass index more than 30. 4.Patients requiring intravenous anaesthetic infusion (for example- propofol, dexmedetomidine) for reducing the intracranial pressure or as a part of SSEP/MEP monitoring protocol. 5.Pregnant patients.

Design outcomes

Primary

Measure	Time frame
To assess the recovery profile in terms of verbal response time, emergence time and extubation time in desflurane based anaesthesia in patients undergoing neurosurgery guided by Patient state index and End tidal anaesthetic concentration monitoring.Timepoint: At discontinuation of anaesthetic agent, at eye opening, at response to verbal commands, at removal of endotracheal tube.	—

Secondary

Measure	Time frame
1. To study the intraoperative hemodynamic variables between the two groups. 2. To assess the total volume of desflurane used.Timepoint: Baseline, post induction, post intubation, post positioning for surgery, 15 mins, 30 mins, 45 mins, 60 mins, 75 mins, 90 mins, 105 mins, 120 mins, 135 mins, 150 mins, 165 mins, 180 mins, post repositioning for extubation, 5 mins post reposition, 10 mins post reposition, 5 mins post extubation.	—

Measure

Time frame

1. To study the intraoperative hemodynamic variables between the two groups. 2. To assess the total volume of desflurane used.Timepoint: Baseline, post induction, post intubation, post positioning for surgery, 15 mins, 30 mins, 45 mins, 60 mins, 75 mins, 90 mins, 105 mins, 120 mins, 135 mins, 150 mins, 165 mins, 180 mins, post repositioning for extubation, 5 mins post reposition, 10 mins post reposition, 5 mins post extubation.

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Countries

India

Contacts

Public ContactDr Geetha L

M S Ramaiah Medical College

geetha4kiran@yahoo.in9611897899

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026