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Comparison of efficiency of ketamine when injected into a blood vessel or injected in a muscle for providing a sleep state for children to undergo MRI scan.

Comparison between intravenous ketamine and intramuscular ketamine sedation for Magnetic Resonance Imaging in pediatric patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/05/033895
Enrollment
108
Registered
2021-05-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z138- Encounter for screening for otherspecified diseases and disorders

Interventions

Control Intervention1: NIL: NIL Control Intervention2: NIL: NIL

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of either gender of age group 2 to 8 year. American society of anaesthesiologists physical status (ASA) I and II patients.

Exclusion criteria

Exclusion criteria: Patients with anticipated difficult airway. Raised Intracranial or intraocular pressure. Vascular aneurysms. History of adverse reaction to ketamine or any other drug used in the study Active seizures.

Design outcomes

Primary

MeasureTime frame
Intravascular and Intramuscular route of ketamine administration are almost equally popular in MRI sedation. However, the use of ketamine in sedation for MRI is highly skewed in favour of intravascular. The two routes have never been compared for sedation in MRI. The sedative efficacy and safety profile and time to discharge in intravenous and intramuscular ketamine are not significantly different. IM method might lead to lesser need of rescue doses.Timepoint: 0-6th month â?? Collection of data and literature review. 6th -7th â?? statistical calculations will be done and result will be provided.

Secondary

MeasureTime frame
To compare any adverse events like bradycardia, hypotension, desaturation, laryngospasm, apnea, excessive salivation, vomiting, emergence delirium, excessive drowsiness, involuntary movements, seizure occurring during the MRI scanning or in the recovery period. To compare the time required for recovery to achieve Modified Andree score equal to 9 or more.Timepoint: 0-6th month â?? Collection of data and literature review. 6th -7th â?? statistical calculations will be done and result will be provided.

Countries

India

Contacts

Public ContactAnuj Jain

All India Institute of Medical Sciences Bhopal

anuj.jain.mln@gmail.com9755702644

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026