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To compare the postoperative pain relief in patients undergoing laparoscopic sterilization with intraperitoneal administration of magnesium sulphate bupivacaine combination and bupivacaine alone

Comparison of the effects of intraperitoneal magnesium sulphate and bupivacaine with that of bupivacaine alone on the duration of postoperative analgesia in laparoscopic sterilization : A prospective , comparative study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/05/033889
Enrollment
70
Registered
2021-05-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Control Intervention1: intraperitoneal 0.25% bupivacaine Vs intraperitoneal Magnesium sulphate & 0.25% bupivacaine: At the end of surgery, patients who - receive intraperitoneal instillation of 40ml o

Sponsors

DR RITHU VARKEY
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: INCLUSION CRITERIA: 1) Females of age 25-40 years 2) American Society of Anesthesiologists (ASA) grade I -II patients 3) Body mass index 18 - 30kg/m2 4) Patients undergoing Laparoscopic sterilization surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria: EXCLUSION CRITERIA 1) Known hypersensitivity to any of the study drugs 2) Patients who had previous abdominal surgery and those on magnesium therapy 3) Patients with respiratory, cardiac , liver and renal disorders 4) Patients who are using analgesics, sedatives, beta blockers and anticonvulsants

Design outcomes

Primary

MeasureTime frame
Primary Objective: 1) To compare the duration of postoperative analgesia among patients undergoing laparoscopic sterilization with intraperitoneal magnesium sulphate plus bupivacaine (MB) and bupivacaine(B) alone Timepoint: baseline,1st hour,2nd hour,4th hour, 6th hour, 8th hour and 12th hour

Secondary

MeasureTime frame
1) To compare the postoperative pain scores 2) To compare the total analgesic intake in first 12hours after surgery 3) To compare the postoperative hemodynamic changes and adverse effects among patients undergoing laparoscopic sterilization with intraperitoneal magnesium sulphate plus bupivacaine (MB) and bupivacaine(B) aloneTimepoint: baseline,1st hour,2nd hour,4th hour, 6th hour, 8th hour and 12th hour

Countries

India

Contacts

Public ContactDR RITHU VARKEY

MALANKARA ORTHODOX SYRIAN CHURCH MEDICAL COLLEGE Medical College

sunutg97@yahoo.co.in9400626526

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026